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The increased expression of ChaC2 is associated with the high expression of p53 (50), and ChaC2 is the upstream regulator of the main antioxidant regulator Nrf2 (78)

Management of respiratory depression may include close observation, supportive measures, and use of opioid overdose reversal agents, depending on the patients clinical status (see OVERDOSAGE)

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Stability of reconstituted research materials

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